AILERON THERAPEUTICS, INC.
490 Arsenal Way, Suite 210
Watertown, MA 02472
July 11, 2019
VIA EDGAR
Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549
| Re: | Aileron Therapeutics, Inc. |
Registration Statement on Form S-3
File No. 333-226650
Request for Acceleration
Ladies and Gentlemen:
Pursuant to Rule 461 promulgated under the Securities Act of 1933, as amended, Aileron Therapeutics, Inc. (the “Registrant”) hereby requests acceleration of the effective date of its Registration Statement on Form S-3 (File No. 333-226650), so that it may become effective at 4:00 p.m. Eastern time on July 15, 2019, or as soon thereafter as practicable, or at such later time as the Registrant or its counsel may orally request via telephone call to the staff.
| Very truly yours, | ||
| AILERON THERAPEUTICS, INC. | ||
| By: | /s/ Donald V. Dougherty | |
| Name: | Donald V. Dougherty | |
| Title: | Senior Vice President, Chief Financial Officer |
| cc: | Stuart M. Falber |
Wilmer Cutler Pickering Hale and Dorr LLP